近期文献报导了心得安对碳水化合物、脂类代谢和凝血系统的影响,但报导的多以短程治疗为主。本文作者将男性缺血性心脏病((?))人长期(2年)不间断地用心得安治疗与未用此药的同期(?)病人的碳水化合物代谢、脂蛋白光谱和凝血系统某些指标的改变进行了对比研究。治疗组75例(?)病人,口服心得安,每日40-320毫克,临床和安静时心电图观察到心率减少15%以上为有效剂量。对照组70例(?)病人,仅用三硝酸甘油和降压剂(萝芙木制剂、(?))两组病人的基本特征是一样的。在全面临床检查的同时,测定了空腹血糖和糖耐量试验(口服葡萄糖法)、总胆固醇、高密度脂蛋白胆固醇、甘油三脂与纤维蛋白原,进行了血栓弹力图检查,并计算血液凝固指数。治疗前和治疗12～24个月时,检查了 Recent literature reported propranolol on carbohydrates, lipid metabolism and coagulation system, but reported mostly in the short-range treatment. The authors of this study report that men with ischemic heart disease (?)) Have long-term (2-year) treatment of carnitine metabolism, lipoprotein spectroscopy, and coagulation system in patients with concomitant (?) The changes in these indicators were compared. The treatment group of 75 patients (?) Patients, oral propranolol, 40-320 mg daily, clinical and resting electrocardiogram observed heart rate reduction of more than 15% as an effective dose. The control group of 70 patients (?) Patients, only the use of trinitrate and antihypertensive agents (rofoodicide, (?)) The basic characteristics of both groups of patients is the same. At the same time of comprehensive clinical examination, the fasting blood glucose and glucose tolerance test (oral glucose method), total cholesterol, high-density lipoprotein cholesterol, triglyceride and fibrinogen were measured, thromboelastography examination was performed and the blood coagulation index . Before treatment and treatment of 12 to 24 months, check