患者女,29岁。入院前6个月曾患上呼吸道感染,3天后治愈。入院前3个月无明显诱因双小腿皮下出现硬性结节,开始黄豆大,逐渐增大可达核桃大,散在分布,胫前较多,有压疼,结节表面皮肤红肿。予青霉素80万 U/d 治疗18天结节缩小,皮肤表面有色素沉着,但其它部位仍有新结节出现。既往体健,月经量多,每次用3～4包纸。于1987年3月17日入院。体检:贫血貌,无黄染。心肺正常,腹软,肝、脾 Patient female, 29 years old. 6 months prior to admission had respiratory infections, 3 days after the cure. 3 months before admission, there was no obvious incentive to appear hard nodules subcutaneous double leg, began big soybeans, walnuts gradually increased, scattered distribution, more tibia, tenderness, nodular skin irritation. To penicillin 800000 U / d treatment of 18 days to narrow the nodules, the skin surface pigmentation, but there are still other parts of the new nodules appear. Past physical health, menstrual volume, each with 3 to 4 packets of paper. March 17, 1987 admission. Physical examination: anemia appearance, no yellow dye. Cardiopulmonary normal, abdominal soft, liver, spleen