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目的观察中西医结合治疗原发性胆汁性肝硬化合并2型糖尿病的临床疗效。方法选择2010年11月—2013年11月我院收治的原发性胆汁性肝硬化合并2型糖尿病患者62例,将其随机分为西医组30例和联合组32例。西医组患者进行单纯西医治疗,联合组患者进行中西医结合治疗,均治疗半年,观察两组患者临床疗效、治疗期间不良反应及血糖控制正常率。结果联合组患者治疗有效率和血糖控制正常率均高于西医组,不良反应发生率低于西医组(P<0.05)。结论中西医结合治疗原发性胆汁性肝硬化合并2型糖尿病能明显提高临床疗效及血糖控制正常率,减少不良反应的发生。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of primary biliary cirrhosis with type 2 diabetes. Methods Sixty-two patients with primary biliary cirrhosis and type 2 diabetes treated in our hospital from November 2010 to November 2013 were randomly divided into 30 cases in the Western medicine group and 32 cases in the combined group. Western medicine group patients were treated with western medicine alone. The patients in combined group were treated with Integrative Chinese and Western medicines for six months. The clinical efficacy, adverse reactions and the normal rate of glycemic control during the treatment were observed. Results The therapeutic efficiency and the normal rate of glycemic control in the combined group were higher than those in the western medicine group, and the incidence of adverse reactions was lower than that in the Western medicine group (P <0.05). Conclusion Integrative treatment of primary biliary cirrhosis with type 2 diabetes can significantly improve the clinical efficacy and the normal rate of glycemic control and reduce the incidence of adverse reactions.