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目的探究中西医联合给药方式对子宫内膜非典型增生患者术后改善治疗效果。方法选择该院2013年1月-2015年12月收治的38例子宫内膜非典型增生患者,对每个患者术前通过宫腔镜进行子宫内膜定点取样进行病理诊断,患者均实施子宫内膜电切术。将患者按照数字分组法随机分为对照组与观察组,每组19例患者,对照组患者术后给予甲羟孕酮治疗,观察组患者给予甲羟孕酮联合中药汤剂的治疗。结果子宫内膜电切术后,仅服用甲羟孕酮治疗的患者出现不规则阴道出血10例(52.6%),乳房胀痛4例(21.1%),胃肠道不适4例(21.1%);甲羟孕酮联合中药方剂治疗的观察组患者出现不规则阴道出血4例(21.1%),出血率低于对照组(P<0.05)。患者术后1、3、6、12个月子宫内膜修复情况两组间比较无统计学差异(P>0.05)。结论子宫内膜非典型增生患者在实施子宫内膜电切术后,中药结合甲羟孕酮的用药治疗可改善患者术后不规则阴道出血的不良反应,对于患者术后宫腔内膜修复无显著影响。
Objective To explore the combination of Chinese and Western medicine on endometrial dysplasia patients after treatment to improve the therapeutic effect. Methods 38 patients with atypical hyperplasia of endometrium admitted from January 2013 to December 2015 in our hospital were enrolled. Each patient was diagnosed pathologically by endoscopic hysteroscopy with fixed point sampling. All patients underwent intrauterine Membrane resection. The patients were randomly divided into control group and observation group according to the digital grouping method. 19 patients in each group and control group were treated with medroxyprogesterone acetate and medroxyprogesterone combined with traditional Chinese medicine decoction in the observation group. Results After endometrial resection, irregular vaginal bleeding occurred in 10 cases (52.6%), breast tenderness in 4 cases (21.1%) and gastrointestinal discomfort in 4 cases (21.1%), ; 4 cases (21.1%) had irregular vaginal bleeding in the observation group treated with medroxyprogesterone plus traditional Chinese medicine and the bleeding rate was lower than that in the control group (P <0.05). There was no significant difference between the two groups in the endometrial repair status at 1, 3, 6 and 12 months after operation (P> 0.05). Conclusion After endometrial resection, the treatment of Chinese medicine combined with medroxyprogesterone acetate can improve the adverse reactions of irregular vaginal bleeding in patients with endometrial atypical hyperplasia after endometrial resection. Significantly affected.