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脑膜癌病(Meningeal carcinomatosis)是指脑和脊髓的软脑膜(软脊膜)内转移瘤细胞弥漫播散或呈多灶状限局性浸润,临床表现为脑、颅神经和脊神经根受损的症状,是颅内转移瘤的一种特殊分布类型。以往认为脑膜癌病是全身性癌瘤比较少见的合併症,近年来的研究指出在癌症病人中脑膜癌病相对地比较常见,值得重视。随着对癌瘤诊断和治疗技术的进步,部份癌症病人的生存期有所延长,发生颅内转移的机会也有增多的趋势,这一点已经引起了人们的注意。Ushio(1977)Rallinger(1979)先后分别建立了脑膜癌病和颅内转移瘤的实验动物模型,为研究这些疾病的病理生理和选择有效的治疗方法提供了新的途径。
Meningeal carcinomatosis (Meningeal carcinomatosis) refers to the diffuse dissemination of diffused or multifocal localized infiltrating cells in the pia mater (brain) of the brain and spinal cord. The clinical manifestations are the symptoms of brain, cranial nerves, and spinal nerve root damage. , is a special type of distribution of intracranial metastases. In the past, meningeal cancer disease was regarded as a relatively rare complication of systemic cancer. Recent studies have pointed out that meningeal cancer disease is relatively common in cancer patients and deserves attention. With the advancement in the diagnosis and treatment of cancer, the survival of some cancer patients has been extended, and the chance of intracranial metastases has also increased. This has already attracted attention. Ushio (1977) Rallinger (1979) established an experimental animal model of meningeal neoplasms and intracranial metastases, which provided a new approach for the study of the pathophysiology of these diseases and the selection of effective treatments.