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目的了解幽门螺杆菌(Helicobacter pylori,HP)感染在维吾尔族与汉族间是否存在民族差异。方法对有消化道症状的392例维吾尔族患HP感染状况与随机抽取同期检查有消化道症状的459例汉族患者进行对比分析。用1%洗必泰或“擦立净”消毒胃镜及活检钳,待胃镜检查后距幽门口5 cm之内取胃窦粘膜2~4块,用于病理组织学检查,方法为G iem sa染色,确定HP的存在。结果维吾尔族和汉族两组患者胃粘膜HP感染有显著性差异(χ2=30.76,P<0.001),维吾尔族女性患者HP阳性率明显高于汉族女性;在疾病分类中慢性浅表性胃炎维吾尔族患者HP阳性率明显高于汉族;维吾尔族间HP感染无性别差异。结论HP感染存在民族差异。
Objective To understand whether there is ethnic difference between Uygur and Han populations in Helicobacter pylori (HP) infection. Methods The prevalence of HP infection in 392 Uygur patients with gastrointestinal symptoms was compared with that of 459 Han patients randomly selected for gastrointestinal symptoms during the same period. With 1% chlorhexidine or “clean the net” disinfection endoscopy and biopsy forceps, gastroscopy to be within 5 cm from the pylorus within 2 cm take antral mucosa 2-4, for histopathological examination, the method for G iem sa Stain, identify HP’s presence. Results The prevalence of HP in gastric mucosa in Uygur and Han patients was significantly different (χ2 = 30.76, P <0.001). The positive rate of HP in Uighur women was significantly higher than that in Han women. In the classification of chronic superficial gastritis Uygur The positive rate of HP in patients was significantly higher than that in Han people. There was no gender difference in Uygur HP infections. Conclusion There are ethnic differences in HP infection.