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目的:观察依达拉奉联合奥扎格雷治疗老年急性脑梗死的疗效。方法:急性脑梗死120例随机分为联用组(依达拉奉加奥扎格雷),依达拉奉组,奥扎格雷组及对照组,每组30例,观察治疗后神经功能改善情况并进行疗效评定。结果:联用组治疗后各时期欧洲卒中量表(ESS)评分均显著高于对照组(P<0.05),21 d及30 d显著高于依达拉奉组和奥扎格雷组(P<0.05),联用组的显效率在30.d显著高于其他组(P<0.05),21 d后有效率高于其他组(P<0.05)。结论:依达拉奉与奥扎格雷联用能显著提高老年急性脑梗死的疗效。
Objective: To observe the efficacy of edaravone and ozagrel in the treatment of senile acute cerebral infarction. Methods: 120 cases of acute cerebral infarction were randomly divided into combined group (edaravone plus ozagrel), edaravone group, ozagrel group and control group, 30 cases in each group, to observe the improvement of neurological function after treatment And efficacy evaluation. Results: The European Stroke Scale (ESS) score was significantly higher in combination group at each time after treatment (P <0.05), and was significantly higher on 21 d and 30 d than that on edaravone and ozagrel (P < 0.05). The effective rate of the combination group was significantly higher than that of the other groups at 30. d (P <0.05), and the effective rate of the combination group was higher than that of the other groups after 21 d (P <0.05). Conclusion: The combination of edaravone and ozagrel can significantly improve the efficacy of acute cerebral infarction in the elderly.