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目的 :建立山楂降压丸真伪鉴别及其非法添加化学成分卡托普利的快速检验方法。方法 :采用TLC法以硅胶GF254为固定相,无水乙醇-氨水(14:1)为展开剂,熏以碘蒸气,置紫外光(254nm)下检视,并将阳性样品用高效液相色谱(HPLC)法进行验证。结果:建立的检验方法简单、快速且成本低,稳定性和重现性均较好,且阳性样品的薄层色谱和HPLC佐证结果一致。结论:本法适合用于山楂降压丸的真伪鉴别及其非法添加卡托普利的快速检测。
Objective: To establish the identification of Hawthorn Antihypertensive Pill and the rapid test method of captopril illegally adding chemical ingredients. Methods: Silica gel GF254 was used as stationary phase and anhydrous ethanol - ammonia (14: 1) as developing solvent. The sample was smoked with iodine vapor and exposed to UV light (254 nm). The positive samples were separated by high performance liquid chromatography HPLC) method to verify. Results: The established assay was simple, rapid and low cost, with good stability and reproducibility. The TLC and HPLC data of the positive samples were consistent. Conclusion: This method is suitable for the authentic identification of Hawthorn Blood Pressure Pills and its rapid detection of captopril illegally added.