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目的评价卵巢癌患者手术前后血清HFA、CA125和SIL-2R检测的临床意义。方法本组针对32例卵巢癌患者及18例健康体检者,进行血清HFA、CA125和SIL-2R检测,并比较分析卵巢癌患者手术前后血清HFA、CA125和SIL-2R水平。结果卵巢癌患者的血清HFA、CA125和SIL-2R水平均显著高于健康体检者(P<0.05);而卵巢癌患者手术后血清HFA、CA125和SIL-2R水平显著低于手术前(P<0.05)。结论血清HFA、CA125和SIL-2R检测应用于卵巢癌诊断及疗效评估,具有重要的临床意义。
Objective To evaluate the clinical significance of serum HFA, CA125 and SIL-2R in patients with ovarian cancer before and after operation. Methods The serum levels of HFA, CA125 and SIL-2R were measured in 32 patients with ovarian cancer and 18 healthy controls. The levels of serum HFA, CA125 and SIL-2R in patients with ovarian cancer before and after operation were compared and analyzed. Results The levels of serum HFA, CA125 and SIL-2R in patients with ovarian cancer were significantly higher than those in healthy subjects (P <0.05). The serum levels of HFA, CA125 and SIL-2R in patients with ovarian cancer were significantly lower than those before operation (P < 0.05). Conclusion Serum HFA, CA125 and SIL-2R levels are useful in the diagnosis and evaluation of ovarian cancer. It has important clinical significance.