据报告,氯苯胍对抑制在马来亚和印度流行的疟疾,效果颇为满意;可是在非洲的观察,则不一致。Covell氏(1949)曾谓其疗效及控制周围血液疟原虫较奎宁及阿的平为差。也有学者报告此药可使疟原虫产生抗药性者。1953—1954年我们在云南双江曾用氯苯胍预防和治疗疟疾,发现其效果较差,且于长期服用后,甚至有治疗失效者,因此将这些结果报告于后。 It has been reported that chlorprozine is quite satisfactory in suppressing the malaria epidemic in Malaysia and India; however, the observations in Africa are inconsistent. Covell’s (1949) has called its efficacy and control of peripheral blood Plasmodium paraquat and quinine worse. Some scholars have reported that this drug can make Plasmodium-resistant people. In 1953-1954, we found that malaria was prevented and treated with mariguanide in Shuangjiang, Yunnan Province and found to be less effective and, after long-term use, even those who failed treatment, so we report these results later.