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目的:探讨加味止嗽散治疗小儿咳嗽(风寒犯肺)的临床疗效。方法:将咳嗽(风寒犯肺型)患儿120例按照随机数字表法分为治疗组和对照组各60例,对照组给予西医常规治疗,治疗组给予加味止嗽散治疗,两组均以7 d为1个疗程。观察两组治疗前后中医证候积分的变化,评价并对比两组的临床疗效和治疗的安全性。结果:治疗后两组的中医证候积分均较治疗前明显改善,治疗组改善情况明显优于对照组,差异有统计学意义P<0.05);治疗组和对照组的临床总有效率分别为98.3%、83.3%,治疗组明显高于对照组,差异有统计学意义(P<0.05)。两组均未发生严重不良反应。结论:加味止嗽散治疗小儿咳嗽(风寒犯肺型)能明显缓解患儿的临床症状,疗效显著,且安全性良好。
Objective: To investigate the clinical curative effect of Jiawei Zhisowan San on the treatment of infantile cough (cold contralateral lung). Methods: A total of 120 children with cough (cold-frostbite type) were divided into treatment group (60 cases) and control group (60 cases) respectively. The control group was given conventional western medicine. The treatment group 7 d for a course of treatment. The changes of TCM syndrome scores before and after treatment were observed, and the clinical efficacy and safety of the two groups were evaluated and compared. Results: After treatment, the TCM syndrome scores in both groups were significantly improved compared with those before treatment, and the improvement in the treatment group was significantly better than that in the control group (P <0.05). The total clinical effective rates in the treatment group and the control group were 98.3% and 83.3% respectively. The treatment group was significantly higher than that of the control group (P <0.05). No serious adverse reactions occurred in both groups. Conclusion: Modified Zhisowan San for treating cough in children (cold contracting lung type) can obviously relieve the clinical symptoms of children with significant curative effect and good safety.