目的:探讨工作场所攻击行为患者静息态功能磁共振技术(R-f MRI)的变化。方法:对23例工作场所攻击行为中施暴者和20名正常者自愿行R-f MRI。探讨工作场所攻击行为中施暴者脑功能异常的神经生物学基础及病理生理机制。结果:与正常对照组比较,工作场所攻击行为施暴者Reho显著增高的脑区是右侧前扣带回、左侧杏仁核、双侧岛叶及海马旁回;Reho显著减低的脑区是右侧眶额叶皮层、右侧中央后回、左侧中央前回。结论:工作场所攻击行为施暴者的额叶、边缘系统(右侧前扣带回、左侧杏仁核、双侧海马旁回)及岛叶的异常与攻击行为之间可能存在特定的联系。 Objective: To investigate the changes of resting state functional magnetic resonance imaging (R-f MRI) in workplace aggressive behavior. METHODS: R-f MRI was performed voluntarily by 23 perpetrators of workplace aggression and 20 normal subjects. To investigate the neurobiological basis and pathophysiological mechanisms of abusive brain dysfunction in workplace aggression. Results: Compared with the normal control group, the areas of Reho significantly increased in the attacker of workplace aggression were right anterior cingulate gyrus, left amygdala, bilateral insula and parahippocampal gyrus; Reho significantly reduced brain area was right Orbital frontal cortex, right central back, left central back. CONCLUSIONS: There may be a specific association between frontal and limbic systems (right anterior cingulate gyrus, left amygdala, bilateral parahippocampal gyrus) and islet anomalies and aggressive behavior in workplace aggression sufferers.