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【目的】应用Gesell测查苯丙酮尿症(phenytkelonuria,PKU)患儿发育商,观察经过治疗的PKU患儿智力发育情况。【方法】Gesell测查32名PKU患儿发育商并与正常同龄儿童进行对照。【结果】经干预治疗的PKU患儿与同龄正常儿比较,在应物能(t=2.81,P<0.01)应人能(t=2.22,P<0.05),差异有统计学意义;而动作能,精细能和言语能无统计学意义(P均>0.05)。【结论】加强高危孕妇的产前诊断及胎儿出生的早期诊断,并进行早期干预治疗,是超高PKU患儿生病质关的有力措施。
【Objective】 Gesell was used to detect the developmental quotient of children with PKU and to observe the mental development of children with PKU. [Methods] Gesell examined 32 infants with PKU and compared them with normal children. 【Results】 Compared with normal children of the same age, the children with PKU who were treated by intervention had a significant difference (t = 2.22, P <0.05) Can, fine and speech can not be statistically significant (P all> 0.05). 【Conclusion】 To strengthen the prenatal diagnosis of high-risk pregnant women and the early diagnosis of fetal birth, and early intervention treatment is a powerful measure for the pathogenesis of hyperkinetic PKU.