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本文报道了一种新型的特异性口服脯氨酰肽链内切酶（ＰＥＰ）抑制剂（ＪＴＰ－４８１９），即左旋一（ＺＳ）一节胺碳酸基一〔（ＺＳ）－２一乙醇酷毗咯烷基工２一毗咯烷甲酸胺，Ｉ期临床的药代动力学和安全性评价结果。ＪＴＰ－４８１９Ｉｔｓ床前药理毒理学研究表明，该药能
In this paper, a new type of specific oral prolyl-endopeptidase (PEP) inhibitor (JTP-4819) Pyrrolidine alkyl pyrrolidine base 2-pyrrolidine, phase I clinical pharmacokinetics and safety evaluation. JTP-4819Its bed pharmacological toxicology studies have shown that the drug can