中草药山慈菇（BulbusIphig6nias，BI）具有败毒抗癌的作用，是一种常用的抗癌中药。但是，山慈菇可诱发体细胞遗传损伤［’］，为进一步了解其对生殖细胞的遗传毒性，采用小鼠精子畸形试验和事丸染色体畸变试验，研究了山慈菇对生殖细胞的致突变性。l材料和方法1．l实验动物白 Bulbus Iphig6nias (BI) is a commonly used anti-cancer medicine. However, Cyperus corniculatus can induce somatic cytogenetic damage [’]. To further understand its genetic toxicity to germ cells, a mouse sperm abnormality test and a chromophore aberration test were performed to study the mutagenicity of Sagittaria sagittifolia on germ cells. Sex. l Materials and Methods 1. l Experimental animal white