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免疫学研究证实,胸腺分泌一组多肽因子调节T细胞亚群的分化成熟并维持免疫平衡状态,从而控制免疫系统的发育和功能。胸腺素对于胸腺功能缺陷的治疗,临床已有确切的疗效。实验研究表明胸腺素能刺激造血和增强免疫力,同时又是有效的辐射防护剂。我们曾在~(60)钴900伦照射小白鼠上观察到胸腺提取物有明显的抗放作用,使平均活存时间延长,活存率提高,并对32磷内照射小白鼠造血系统有保护作用。本文主要目的在于验证胸腺素5组分对900伦照射小鼠的抗放效果。材料与方法1.动物:本所繁殖的昆明种小白鼠80只,
Immunological studies have confirmed that the thymus secretes a group of polypeptide factors that regulate the maturation of T cell subsets and maintain immune balance, thereby controlling the development and function of the immune system. Thymosin has been clinically proven to be effective in the treatment of thymus functional defects. Experimental studies have shown that thymosin can stimulate hematopoiesis and enhance immunity, and at the same time it is an effective radiation protection agent. We have observed significant anti-resistance effects of thymic extracts on ~(60) Cobalt-900-enhanced white mice, resulting in prolonged mean survival time, increased survival, and protection of hematopoietic system in 32-phosphoirradiation mice. effect. The main purpose of this article is to verify the anti-radiation effect of thymosin 5 components on 900-len exposure mice. Materials and Methods 1. Animals: There were 80 Kunming species of mice reproduced in this institute.