氧化应激在糖尿病及其并发症的发生发展中极为重要,胰岛细胞损伤、胰岛素抵抗、糖基化终末产物形成、蛋白激酶C途径、多元醇通路、己糖胺途径均与氧化应激产生过多的自由基密切相关,因此,减轻氧化应激损伤,有利于糖尿病及其并发症的防治。本文主要就近5年来在糖尿病治疗领域各类中药抗氧化作用研究进展作一综述。 Oxidative stress is extremely important in the development of diabetes mellitus and its complications. Islet cell injury, insulin resistance, formation of advanced glycation end products, protein kinase C pathway, polyol pathway and hexosamine pathway are all associated with oxidative stress Too many free radicals are closely related, therefore, to reduce oxidative stress damage, is conducive to the prevention and treatment of diabetes and its complications. This article mainly reviews the research progress of various Chinese antioxidants in the field of diabetes mellitus in recent 5 years.