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采用ＧＣ／ＭＳ单离子检测的内标法测定了联苯苄唑溶液剂和霜剂１０、３０、１００ ｍ ｇ 三个剂量在家兔感染皮肤上连续用药１５ ｄ 后的血药浓度，并在１０ ｍ ｇ 剂量下与健康皮肤作了比较。
The plasma concentrations of bifonazole solution and cream at doses of 10, 30 and 100 m g were determined by GC / MS single-ion method after 15 days of continuous infection on the skin of rabbits. Compared with healthy skin at a dose of 10 m g,