氟康唑为二唑类第三代抗真菌药物,具有广谱抗真菌作用,主要用于念珠菌病及隐球菌病。近年来国内有文献报道,本品可致肝功能损害,现概述如下:余秉翔等报道,患男,50岁,因右下肺感染给予氟康唑100mg治疗,bid,共8天,第9天患者出现恶心、厌油、食欲不振,查肝功能示ALT 133U/L、AST115U/L,并逐渐加重,再查肝功能示ALT 379U/L、 Fluconazole is the third generation of diazole antifungal agents, with broad-spectrum antifungal effect, mainly for candidiasis and cryptococcosis. In recent years, domestic literature reports that this product can cause liver damage, are summarized as follows: Yu Bingxiang other reports, suffering from male, 50 years old, due to lower right lung infection given fluconazole 100mg treatment, bid, a total of 8 days, the first 9 days Patients with nausea, tired of oil, loss of appetite, check liver function showed ALT 133U / L, AST115U / L, and gradually increased, and then check the liver function showed ALT 379U / L,