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目的探讨心电图额面P电轴垂直化在慢性阻塞性肺疾病(COPD)患者筛查与诊断中的意义.方法纳入120例慢阻肺患者/80例非慢阻肺患者作为研究对象，比较两组心电图P电轴的变化，并分析P电轴垂直化与慢阻肺患者FEV1的关系.结果P电轴垂直化程度在慢阻肺患者显著高于对照组(＜0.01)；P电轴垂直化程度与慢阻肺患者FEV1呈显著负相关(＜0.01).结论 P电轴垂直化可作为慢阻肺的独立筛查指标，并可用于评估其严重程度.“,”Objective To evaluate the Screening and diagnostic values of vertical P-wave axis in Chronic Obstructive Pulmonary Disease. Methods Two hundreds patients of age>45 years included to the study. Patients were in sinus rhythm, with normal ejection fraction and heart chamber sizes. Their pulmonary function tests and electrocardiograms were obtained at same day. 120 people were diagnosed with COPD based on pulmonary function tests. We analyzed electrocardiograms to determine the P wave axis and divided 106 patients of COPD into two categories depending on the frontal P- axis, >78 degrees, 60~78 degrees.Results Prevalence of COPD with vertical P-axis was strikingly higher than in the control group: 86.9% vs 6.4%. Prevalence of severe COPD was strikingly higher in patients with P-axis > 78° as compared to the group with P-axis 60°-78°: 93.4% vs 6.7%. Conclusion Vertical P-wave axis is a useful screening criteron for COPD and degree of verticalisation provides a gross quantification of the disease.