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目的探讨嗜酸细胞性胃肠炎(Eosinophilic gastroenteritis,EG)的临床特点、诊断、治疗及其误诊原因。方法 7例患者中有5例根据患者的病史、临床表现、实验室检查、多次内镜检查确诊为EG并用激素治疗,另2例术前诊断为瘢痕性幽门梗阻行胃大部切除术后病理诊断为EG,术后用激素治疗。结果 7例患者均痊愈出院,其中1例术后发生胃排空障碍、吻合口溃疡,经保守治疗痊愈。结论 EG临床表现无特异性,内镜表现多为黏膜片状糜烂和水肿,内镜应行多点活检,激素疗效好,对肌层病变型伴有幽门梗阻患者可以手术治疗。
Objective To investigate the clinical features, diagnosis, treatment and causes of misdiagnosis of eosinophilic gastroenteritis (EG). Methods Five of the seven patients were diagnosed as EG with hormone therapy according to the patient’s medical history, clinical manifestations, laboratory tests and multiple endoscopy. The other two cases were diagnosed as cicatricial pyloric obstruction preoperatively underwent subtotal gastrectomy Pathological diagnosis of EG, postoperative hormone therapy. Results All the 7 patients were cured and discharged. Among them, 1 patient developed gastric emptying and anastomotic ulcer after operation, and healed by conservative treatment. Conclusions The clinical manifestations of EG are nonspecific. The endoscopic findings are mostly mucoperiosteal erosion and edema. Endoscopic multi-biopsy should be performed. The hormones have a good curative effect. Patients with muscular dysplasia with pyloric obstruction may be treated surgically.