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胆囊疾患的流行病学国际间差异很大,基于26个国家尸检的综述,其发病由加纳的0%到瑞典的37.1%。本文对本病的一些有关因素进行前瞻性研究。材料及方法研究对象是于1900～1919年出生,住在夏威夷群岛的日裔美国人共7 831名。调查其职业、教育、宗教、吸烟史、饮食习惯以及身体活动量。结果7831名男性共152 831人年的随访中,经外科、组织学或影象学确诊有471名患有胆囊疾病,其中350名(74%)有症状。经过多变量分析,发现下列因素与胆囊疾病有关:肥胖、体重指数与胆囊疾病呈正相关;身高与其呈
The epidemiology of gallbladder disorders varies widely across the world, based on a review of autopsy in 26 countries, with incidence ranging from 0% in Ghana to 37.1% in Sweden. In this paper, some of the factors related to this disease were prospectively studied. Materials and Methods Subjects were born in 1900-1919, a total of 7 831 Japanese Americans living in the Hawaiian Islands. Investigate their occupation, education, religion, smoking history, eating habits, and physical activity. Results Of a total of 7831 men enrolled in a total of 152,831 person-years, 471 patients with gallbladder disease were diagnosed by surgery, histology or imaging, of whom 350 (74%) had symptoms. After multivariate analysis, the following factors were found to be associated with gallbladder disease: obesity, body mass index and gallbladder disease were positively correlated; height and its was