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目的了解中山市小榄镇儿童乙肝病毒标志物携带模式,为乙型肝炎的防治工作提供依据。方法采用整群抽样的方法,抽取2008年1月1日至6月30日在小榄人民医院体检的7月龄至7岁儿童的乙肝“两对半”(即HBsAg、HBsAb、HBeAg、HBeAb和HBcAb 5项标志物)检测结果进行统计分析。结果共检测3 396名儿童,其HBsAg携带率为1.59%,且随年龄的增长呈上升趋势(P<0.01);HBsAb阳性率为60.48%,阳性率随年龄增长呈下降趋势(P<0.01);37.81%的儿童乙肝“两对半”均为阴性。结论小榄镇7月龄至7岁儿童HBsAg携带率低于全国平均水平,但乙肝“两对半”的阴性率较高,应继续推广乙肝疫苗的加强免疫和“两对半”的检测工作,加大乙肝的综合防治力度。
Objective To understand the mode of carriage of HBV markers among children in Xiaolan Town, Zhongshan City, and to provide a basis for the prevention and treatment of hepatitis B. Methods A cluster sampling method was used to collect hepatitis B virus (HBsAg, HBsAb and HBeAg) in children aged 7 months to 7 years who were examined at Siu Lam People’s Hospital from January 1, 2008 to June 30, , HBeAb and HBcAb five markers) test results for statistical analysis. Results A total of 3 396 children were detected. The HBsAg carrier rate was 1.59% and increased with age (P <0.01). The positive rate of HBsAb was 60.48%. The positive rate of HBsAb decreased with age (P <0.01) ; 37.81% of children with hepatitis B “two pairs of semi-” are negative. Conclusion The carrying rate of HBsAg in children aged 7 months to 7 years in Xiaolan Town is lower than the national average, but the negative rate of HBsAg is relatively high. We should continue to promote the enhanced immunity of hepatitis B vaccine and double- "Testing, increase the comprehensive prevention and treatment of hepatitis B efforts.