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目的:研究埃索美拉唑与奥美拉唑三联疗法治疗胃溃疡的疗效以及安全性。方法:选取我院消化科2013.5~2016.5期间收治的58例胃溃疡患者,采用随机分组的方式分为实验组和对照组,每组29例,对照组患者给予奥美拉唑进行治疗,实验组患者给予埃索美拉唑进行治疗,比较两组患者的不良反应率、总有效率以及Hp转阴率。结果:实验组胃溃疡患者不良反应率3.45%,总有效率96.55%,Hp转阴率96.55%,所有数据与对照组相比均有优势(P<0.05)。结论:采用埃索美拉唑治疗胃溃疡疗效好,不良反应率低,安全性高。
Objective: To study the efficacy and safety of triple therapy with esomeprazole and omeprazole in the treatment of gastric ulcer. Methods: Fifty-eight patients with gastric ulcer were enrolled in the Department of Gastroenterology from January 2013 to May 2016. The patients were randomly divided into experimental group and control group, with 29 cases in each group. Patients in the control group were given omeprazole for treatment. The experimental group Patients were given esomeprazole for treatment. The adverse reaction rate, total effective rate, and Hp negative rate were compared between the two groups. Results: The adverse reaction rate of gastric ulcer in experimental group was 3.45%, the total effective rate was 96.55%, and the negative conversion rate of Hp was 96.55%. All the data had advantages compared with control group (P <0.05). Conclusion: Esomeprazole treatment of gastric ulcer with good efficacy, low adverse reaction rate and high safety.