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用ＮＡＤＰＨ黄递酶组织化学染色法（ＮＤＰ）观察了正常成年大鼠、金黄地鼠和家兔视网膜内一氧化氮合酶（ＮＯＳ）的分布，并比较了３种不同动物的区别。结果显示，在视网膜内ＮＯＳ阳性神经元主要为分布于内核层的无长突细胞、节细胞层的移位无长突细胞和少数节细胞。不同种类动物的视网膜内，ＮＯＳ阳性细胞的配布、密度和细胞形态均有差异。大鼠视网膜内ＮＯＳ阳性细胞多属于内核层无长突细胞和节细胞层移位无长突细胞，偶见于视网膜节细胞。金黄地鼠视网膜内ＮＯＳ阳性细胞分布于内核层无长突细胞和节细胞层的移位无长突细胞，ＮＯＳ阳性节细胞的数目比大鼠多。家兔视网膜内ＮＯＳ阳性细胞仅见于内核层无长实细胞。金黄地鼠视网膜ＮＯＳ阳性细胞分市密度最大，平均为１４１．４２个细胞／ｍｍ２；大鼠和家兔视网膜ＮＯＳ阳性细胞分布密度相似，分别平均为３５．９８个细胞／ｍｍ２和４１．５４个细胞／ｍｍ２。实验结果提示，一氧化氮可能作为一种重要的神经递质参与视觉信息的形成、整合和传递。
The distribution of nitric oxide synthase (NOS) in the retina of normal adult rats, golden hamster and rabbits was observed by NADPH diaphorase histochemical staining (NDP). The differences of three kinds of animals were compared. The results showed that NOS positive neurons in the retina were mainly amacrine cells distributed in the inner nuclear layer, and the stratum corneum cells were free of amacrine cells and few ganglion cells. Different types of animals within the retina, NOS-positive cells with the distribution, density and cell morphology are different. NOS positive cells in the retina mostly belong to the amacrine amacrine cells and ganglion cell transplants amacrine cells, occasionally in the retinal ganglion cells. NOS positive cells in the retina of golden hamster were located in the apical layers of amacrine cells and ganglion cells, and there were more NOS positive cells than rats. Rabbit retina NOS positive cells found only in the inner nuclear layer without long cells. The average density of NOS positive cells in the retina of golden hamster was 141.42 cells / mm2. The density of NOS positive cells in the retina of rats and rabbits were similar, with an average of 35.98 cells / mm2 and 41.54 Cells / mm2. The experimental results suggest that nitric oxide may participate in the formation, integration and transmission of visual information as an important neurotransmitter.