整合素是细胞表面的一种黏附因子,它通过介导细胞与细胞,细胞与细胞外基质间的相互作用参与细胞的多种生理活动。整合素与肿瘤的发生、发展以及侵润转移关系十分密切。近年来正成为研究的重点和热点,而卵巢癌仍旧是妇科恶性肿瘤疾病的主要死亡原因。现仅就整合素与卵巢癌的研究现状进行综述。 Integrins are adhesion molecules on the cell surface that participate in various physiological activities of the cell by mediating cell-cell, cell-extracellular matrix interactions. Integrin and tumor occurrence, development and invasion and metastasis are closely related. In recent years, research has become the focus and hot spots, and ovarian cancer is still the leading cause of death of gynecological malignancies. Now only integrin and ovarian cancer research status are reviewed.