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RU486是一类合成甾体衍生物。它与孕酮(P)及糖类皮质激素受体相结合从而阻止它们的功能。目前它已被广泛用来终止早期妊娠和性交后避孕。研究发现在妇女月经周期的卵泡期给RU486 25mg/日,可使卵泡发育受阻并延迟黄体化,故试将RU486作为一种口服避孕药(OC)。本文提出的方案是:于月经周期第1~21天给予RU48625mg/日,于周期第22~31天给予合成孕激
RU486 is a class of synthetic steroid derivatives. It binds to progesterone (P) and glucocorticoid receptors to prevent their function. It has been widely used to terminate early pregnancy and post-conception contraception. The study found that women in the menstrual cycle of follicular to RU486 25mg / day, can obstruct the development of follicles and delayed lutealization, so try RU486 as an oral contraceptives (OC). The proposed program is: given RU48625mg / day on the first to 21st days of the menstrual cycle, in the cycle of 22 to 31 days given synthetic pregnant stimulus