范可尼综合征是一组多发性近端肾小管功能障碍性疾病,包括氨基酸、葡萄糖、磷酸和氢碳酸离子的再吸收障碍。尿中出现多种氨基酸、葡萄糖、尿磷大量流失和尿偏碱性。常伴有肾小管性蛋白尿,肾的浓缩功能和保钾保钠功能降低,继而出现低磷血症和代谢性酸中毒。 Fanconi syndrome is a group of multiple proximal renal tubular dysfunction diseases, including the reabsorption of amino acids, glucose, phosphoric acid and hydrogen carbonate ions. A variety of amino acids appear in the urine, glucose, urine loss of large amounts of phosphorus and alkaline urine. Often accompanied by tubular proteinuria, renal function and potassium-conserving sodium to reduce sodium, followed by hypophosphatemia and metabolic acidosis.