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目的:对中药的使用现状、出现的安全性问题及引起不良反应的原因等进行分析研究,为如何预防、避免和减少中药引起的不良反应提供依据,提高中药使用的合理性和安全性。方法:拟采用回顾性研究方法,通过查阅统计中山市某中医院2011年内临床使用中药发生的不良反应病历资料,对中药的使用情况进行统计分析,探讨其合理性、安全性及影响因素。结果:影响中药的安全使用是多方面因素造成的:①老年人居多占总数的42.3%;②注射剂引起不良反应占总数76.9%;③静脉滴注引起不良反应占总数92.3%;④联合用药引起不良反应占总数67.3%。结论:正确、合理使用中药及选择合理的给药途径可以减少药源性疾病的发生。
OBJECTIVE: To analyze the current situation of using traditional Chinese medicine, the safety problems and the causes of adverse reactions, and to provide basis for preventing, avoiding and reducing adverse reactions caused by traditional Chinese medicine and to improve the rationality and safety of traditional Chinese medicine. Methods: A retrospective study was conducted to investigate the use of traditional Chinese medicine (TCM) by statistical analysis of adverse medical records of a traditional Chinese medicine used in a Chinese medicine hospital in Zhongshan City in 2011 to investigate its rationality, safety and influencing factors. Results: The safe use of Chinese medicine was caused by many factors: (1) the elderly accounted for 42.3% of the total; (2) the adverse reactions caused by injection accounted for 76.9% of the total; (3) the adverse reactions caused by intravenous drip accounted for 92.3%; (4) Adverse reactions accounted for 67.3% of the total. Conclusion: Correct and rational use of traditional Chinese medicine and selection of reasonable routes of administration can reduce the occurrence of drug-induced diseases.