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麻风病免疫方面许多的研究是测定末梢血中的淋巴细胞和巨噬细胞。单克隆抗体也曾用于免疫病理的观察。本文用从肉芽肿内提取细胞的方法来了解肉芽肿形成的免疫学机制。取21例(BT/TT11例;BL/LL10例)未治疗麻风病人皮损活检(15×5mm),一半做常规病理检查;另一半研碎,分离细胞,制成悬液,再作涂片。用各种单克隆抗体(OKT11,识别全部T细胞;OKT8,识别Ts;OKIa,识别有活性的T细胞、巨噬细胞和B细胞;Leu3a,识别TH)及免疫荧光
Much of the research on leprosy immunity is the determination of lymphocytes and macrophages in peripheral blood. Monoclonal antibodies have also been used for immunopathology observation. This article uses methods of extracting cells from granulomas to understand the immunological mechanism of granuloma formation. Take 21 cases (11 cases of BT / TT; 11 cases of BL / LL) untreated leprosy skin lesions biopsy (15 × 5mm), half do routine pathological examination; the other half crushed, the cells were separated, made suspension, and then smear . OKT8, recognition of Ts; OKIa, recognition of viable T cells, macrophages and B cells; Leu3a, recognition of TH), and immunofluorescence with various monoclonal antibodies (OKT11, recognition of all T cells;