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目的:比较探讨生长抑素制剂(善宁)与垂体后叶素治疗肝硬化并发上消化道出血的疗效。方法:将40例上消化道出血患者随机分为两组:A组20例,应用生长抑素八肽(善宁)治疗;B组20例,应用垂体后叶素治疗。结果:A组止血效果优于B组,有显著性差异(P<0.05)。结论:生长抑素制剂治疗肝硬化上消化道出血的临床疗效优于垂体后叶素。
Objective: To compare the curative effect of somatostatin preparations (Shanning) and pituitrin on cirrhosis with upper gastrointestinal hemorrhage. Methods: Forty patients with upper gastrointestinal bleeding were randomly divided into two groups: group A (n = 20) and treatment with somatostatin octapeptide (group Shan). Group B (n = 20) received pituitrin treatment. Results: The effect of hemostasis in group A was better than that in group B (P <0.05). Conclusion: The clinical efficacy of somatostatin in the treatment of cirrhosis and upper gastrointestinal bleeding is superior to that of pituitary.