目的 本次试验将采用前部玻璃体切割联合房角分离术对白内障手术后恶性青光眼患者实施临床治疗观察，分析治疗的有效率和安全性?方法 本次试验选取前来本院就诊的患者为研究对象，时间为2020年1月至2021年7月，均诊断为白内障手术后恶性青光眼，在自愿参与试验调查的基础上选取了54例患者作为调研对象，其均采用前部玻璃体切割联合房角分离术开展治疗，观察患者的眼压?前房深度以及视网膜和矫正视力等相关指标结果?结果 从手术后3个月的情况上看，患者在矫正视力?眼压以及前房深度上分别为(0.58±0.12)?(15.32±“,”Objective To observe the clinical treatment of malignant glaucoma after cataract surgery by anterior vitrectomy combined with anterior chamber angle separation， and to analyze the efficacy and safety of the treatment. Methods The patients who came to our hospital from January 2020 to July 2021 were all diagnosed as malignant glaucoma after cataract surgery. On the basis of voluntary participation in the experimental investigation， 54 patients were selected as the research subjects. All patients were treated with anterior vitrectomy combined with angle separation. The intraocular pressure， anterior chamber depth， retina and corrected visual acuity were observed. Relevant indicators such as results. Results Three months after operation， the corrected visual acuity， intraocular pressure and anterior chamber depth of the patients were (0.58±0.12)， (15.32±2.36) mm Hg and (3.26±0.57) mm， respectively， which were significantly different from those before operation (P <0.05). At the same time， the complications of the patients were observed. Among them， there were 5 cases of ciliary body detachment. The incidence rate was 9.3%. After treatment， the complications were improved. In the survey of treatment satisfaction， the patients gave a higher evaluation， that is， the score was (91.60±3.70). Conclusion The anterior vitrectomy combined with anterior chamber angle separation is effective in the treatment of malignant glaucoma after cataract surgery. It can improve the intraocular pressure， anterior chamber depth， retina and corrected visual acuity， promote the formation of anterior chamber and the outflow of aqueous humor.