锰是人体必需的微量元素之一,是多种酶的成分及辅因子,在长期非肠道补充营养(TP)情况下,易发生缺锰症。因此临床迫切需要硫酸锰注射液,本文对其处方、制备、稳定性、安全性等进行了研究,并制订了质量标准。对应用原子吸收光度法和可见分光光度法进行含量测定作了比较,证明了可见分光光度法的可靠性、供国内应用参考。 Manganese is one of the trace elements essential to the human body, is a variety of enzyme components and cofactors, in the case of long-term non-intestinal nutritional supplements (TP), prone to manganese deficiency. Therefore, the urgent need of clinical manganese sulfate injection, the paper on its prescription, preparation, stability, safety, etc. were studied, and set the quality standards. The application of atomic absorption spectrophotometry and visible spectrophotometry were compared to determine the content, which proved the reliability of visible spectrophotometry for domestic application reference.