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1名62岁甲状旁腺癌妇女,已呈现肺、胸膜转移与严重骨病。18个月来血钙极高(35~42mmol/L),常规降钙措施无效。作者首次报告用免疫接种法控制未发生骨转移的高血钙。方法是制备出含200μg合成的人与牛甲状旁腺素1~34(PTH1—34)肽段...
A 62-year-old woman with parathyroid carcinoma has developed lung, pleural metastases, and severe bone disease. Blood calcium was extremely high in 18 months (3 5 4 2 mmol/L), and conventional calcium reduction measures were ineffective. The authors report for the first time the use of immunization to control hypercalcemia without bone metastases. The method is to prepare 200μg synthetic human and bovine parathyroid hormone 1~34 (PTH1-34) peptides...