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器官功能衰竭是导致重症急性胰腺炎（SAP）患者死亡的重要因素。近年得益于对SAP病理生理研究的进一步深入和经验技术的不断积累，在SAP患者器官功能衰竭诊断治疗方面取得了长足的进步。介绍了SAP并发器官功能衰竭的临床特点和SAP应注意重点加强的治疗措施。目前认为SAP一旦发生容易造成器官功能衰竭，及时规范的治疗能缩短病程，显著降低病死率。“,”Organ failure is an important factor causing death in patients with severe acute pancreatitis (SAP).In recent years,thanks to the further study of pathophysiology of SAP and the continuous accumulation of experience and technology,substantial progress has been made in the diagnosis and treatment of SAP complicated by organ failure.The clinical features of SAP complicated by organ failure and the measures to be strengthened in the treatment of SAP are summarized.Currently,it is thought that organ failure tends to appear once SAP occurs,so timely,standardized treatment can shorten the course of disease and significantly reduce mortality.