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作者将硝硫氰胺硬胶囊、硝硫氰胺微囊片、硝硫氰胺胶丸三种不同制剂,以转篮法进行溶出速度的测定。实验结果发现三者的体外释放速度有极显著的差异。硬胶囊t(50)最快(9分钟)、微囊片次之(35分钟)、胶丸最慢(118分钟)。
The author will nitrocellulose hard capsule, nitrocytisine microcapsule tablets, nitrocytankrene capsules three different formulations, to basket method for dissolution rate determination. The experimental results showed that the three in vitro release rate has a very significant difference. Hard capsule t (50) the fastest (9 minutes), microencapsulated (35 minutes), the slowest capsules (118 minutes).