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目的评价PCR检测技术在宫颈癌筛查中的应用价值。方法选择2007年11月～2008年11月妇科门诊病人1625例并对其肿瘤组织或分泌物进行HPV检测。结果HPV阳性438例,发生率67.2%,各种病理类型的宫颈病变中HPV感染率分别为:慢性宫颈炎46.8%,CIN92.5%,宫颈癌100%,随着宫颈病变严重程度的增加,HPV的感染率也增高,它们之间的差异有统计学意义(P<0.05)。结论HPV感染与宫颈病变严重程度密切相关;PCR检测技术在宫颈癌筛查中有重要作用。
Objective To evaluate the value of PCR detection in cervical cancer screening. Methods A total of 1625 gynecological outpatients from November 2007 to November 2008 were selected for HPV testing of tumor tissues or secretions. Results HPV positive 438 cases, the incidence rate of 67.2%, various pathological types of cervical lesions HPV infection rates were: 46.8% of chronic cervicitis, CIN92.5%, 100% of cervical cancer, with the severity of cervical lesions increased, HPV infection rate also increased, the difference between them was statistically significant (P <0.05). Conclusion HPV infection is closely related to the severity of cervical lesions; PCR detection plays an important role in screening cervical cancer.