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目的 探讨两种麻醉方式对腹腔镜下行宫颈癌切除术老年患者认知功能的影响.方法 将武警海警总队医院2016年8月至2018年4月收治的腹腔镜下行宫颈癌切除术老年患者60例按照床位号奇偶数进行分组,分为对照组和观察组各30例.对照组使用单纯静脉麻醉(丙泊酚泵注),观察组使用静吸复合麻醉(七氟烷吸入加丙泊酚泵注),比较两组的麻醉效果、简易智能精神状态检查量表(MMSE)评分、蒙特利尔认知评估表(MoCA)评分及认知功能障碍发生率.结果 观察组的麻醉见效时间[(1.62±0.30)min]、拔管时间[(15.68±3.26)min]、患者苏醒时间[(8.69±3.68)min]均比对照组短[依次为(4.68±0.91)min、(27.46±4.03)min、(20.36±4.58)min],均差异有统计学意义(均P0.05),术后2 h、6 h两组的MMSE评分均差异有统计学意义(均P<0.05),观察组高于对照组(均P0.05);术后2 h、6 h、1 d观察组的MoCA评分均高于对照组,均差异有统计学意义(均P<0.05);观察组患者的认知功能障碍发生率[6.67％(2/30)]比对照组[26.67％(8/30)]低,差异有统计学意义(P<0.05).结论 相比于单纯静脉麻醉,给予腹腔镜下行宫颈癌切除术老年患者静吸复合麻醉,具有较好的麻醉效果,且能降低患者认知功能障碍发生率,值得临床进一步推广使用.“,”Objective To investigate the effects of two anesthetic modes on cognitive function in elderly patients undergoing laparoscopic cervical cancer resection .Methods From August 2016 to April 2018,60 elderly patients undergoing laparoscopic cervical cancer resection in the General Hospital of Armed Police were divided into control groupand observation group according to odd and even of bed number ,with 30caese in each group.Intravenous anesthesia was used in the control group ,and intravenous anesthesia combined with inhalation anesthesia was used in the observation group.The anesthetic effect,MMSE score,MoCA score and the incidence of cognitive dysfunction were compared between the two groups.Results The anesthesia effect time,extubation time and recovery time of the observation group were (1.62 ±0.30) min,(15.68 ±3.26) min,(8.69 ±3.68) min,respectively,which were significantly shorter than those of the control group [(4.68 ±0.91)min,(27.46 ±4.03)min,(20.36 ±4.58)min] (all P<0.05).There were no statistically significant differences in MMSE score and MoCA score between the two groups before operation (all P<0.05),and there was statistically significant difference in MMSE score between the two groups at 2 h and 6 h after operation (all P<0.05).The MMSE score in the observation group was higher than that in the control group(all P0.05).At 2 h,6 h,1 d after operation,the MoCA scores in the observation group were significantly higher than those in the control group (all P<0.05).The incidence of cognitive dysfunction in the observation group was 6.67％(2/30), which was significantly lower than 26.67％( 8/30 ) in the control group ( P <0.05 ).Conclusion Compared with intravenous anesthesia alone , intravenous anesthesia combined with inhalation anesthesia for elderly patients undergoing laparoscopic cervical cancer resection has a good anesthetic effect and can reduce the incidence of cognitive dysfunction ,which is worthy of further application in clinical practice .