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用THPRIA药盒,对101名正常人的血、尿THP进行检测:血THP为159.89±5l.57ng/ml,尿THP为28.84±14.99mg/24h,与国内外学者报道相近。对298例8种肾脏病患者血、尿THP值进行了检测,尿THP值均比正常人有明显下降。经统计学处理,慢性肾衰、间质性肾炎、慢性肾炎、狼疮性肾炎、糖尿病性肾病、尿路感染等7种疾患均有非常显著差异;而血中THP值只有前4种有非常显著差异,其余无差异,提示尿样检测优于血样检测。在对279例肾病患者检测血、尿THP值的同时,还检测了血、尿β_2-MG、尿Alb、血液尿素氮(BUN)和血Cr。血、尿THP值对各种肾病的总异常率低于尿Alb和β_2-MG,但高于BUN和血Cr。
THPRIA kit, 101 normal blood, urine THP were detected: blood THP was 159.89 ± 5l. 57ng / ml, urinary THP was 28.84 ± 14.99mg / 24h, similar to that of domestic and foreign scholars. The blood and urine THP values of 298 patients with 8 kinds of nephropathy were detected, and the THP value of urine was significantly lower than that of normal people. Statistically, seven kinds of diseases such as chronic renal failure, interstitial nephritis, chronic nephritis, lupus nephritis, diabetic nephropathy and urinary tract infection all had very significant differences; only the first four blood THP values were very significant Differences, the rest no difference, suggesting that urine samples better than blood test. Serum and urinary β_2-MG, urinary Alb, blood urea nitrogen (BUN) and blood Cr were also detected in 279 cases of nephropathy patients with blood and urine THP. The total abnormal rate of blood and urine THP for various nephropathy was lower than that of urinary Alb and β_2-MG, but higher than BUN and blood Cr.