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目的研究经鼻持续气道正压通气(NCPAP)对急性低氧性呼吸衰竭患儿氧合状态的影响。方法回顾性分析2010年10月-2012年10月我院急性低氧性呼吸衰竭患儿40例的临床资料。结果经治疗,40例患儿在短时间内SaO2和PaO2均得到不同程度的改善,治愈32例,NCPAP应用时间平均5.6±2.7d。无效8例,后改为有创机械通气治疗,年龄均<3个月,且5例合并急性充血性心力衰竭。结论 NCPAP治疗儿童急性低氧性呼吸衰竭疗效较好,如治疗24h后平均氧合指数无明显改善,要根据实际情况予以机械通气。
Objective To investigate the effect of nasal continuous positive airway pressure (NCPAP) on the oxygenation status in children with acute hypoxemic respiratory failure. Methods The clinical data of 40 children with acute hypoxic respiratory failure in our hospital from October 2010 to October 2012 were retrospectively analyzed. Results After treatment, SaO2 and PaO2 in 40 cases were improved to some extent in 32 cases, 32 cases were cured and the average time of application of NCPAP was 5.6 ± 2.7 days. 8 cases were ineffective, and then changed to invasive mechanical ventilation. All patients were less than 3 months old, and 5 cases had acute congestive heart failure. Conclusion NCPAP treatment of children with acute hypoxemic respiratory failure better effect, such as 24h after treatment, the average oxygenation index no significant improvement, according to the actual situation to be mechanical ventilation.