论文部分内容阅读
目的探讨单纯收缩期高血压(ISH)患者颈动脉病变与动态血压监测指标的相关性。方法将高血压病患者231例分为ISH组和非单纯收缩期高血压(NISH)组,同时设54例正常对照组,对3组对象行颈动脉超声和动态血压测定。结果ISH组颈动脉内膜中膜厚度(IMT)水平高于NISH组(P<0.05),并显著高于对照组(P<0.01);ISH组收缩压(SBP)、脉压(PP)、脉压指数(PPI)均显著大于NISH组和对照组(P<0.01);Logistic回归分析显示,ISH组患者颈动脉硬化的发生与其PPI、SBP、PP相关,与PPI的相关性最为显著(P=0.008)。结论ISH患者颈动脉内膜增厚严重,与PPI、SBP和PP水平呈正相关。
Objective To investigate the correlation between carotid artery disease and ambulatory blood pressure monitoring in patients with isolated systolic hypertension (ISH). Methods 231 patients with essential hypertension were divided into ISH group and non-isolated systolic hypertension group (NISH). At the same time, 54 normal control subjects were enrolled. Carotid artery ultrasound and ambulatory blood pressure were measured in 3 subjects. Results The carotid intima-media thickness (IMT) in ISH group was significantly higher than that in NISH group (P <0.05), and significantly higher than that in control group (P <0.01). The systolic blood pressure (SBP), pulse pressure Logistic regression analysis showed that the incidence of carotid atherosclerosis correlated with PPI, SBP and PP in ISH group, and the correlation with PPI was the most significant (P <0.01) = 0.008). Conclusions Carotid artery intima thickening is serious in patients with ISH, which is positively correlated with PPI, SBP and PP levels.