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目的:观察中药“白黄液”预防脑出血并发应激性溃疡出血的疗效。方法:脑出血患者110例,随机分为观察组61例及对照组49例,观察组在对照组常规治疗的基础上加口服或胃管注入“白黄液”。结果:观察组并发应激性溃疡出血5例(8.2%),死亡4例(6.6%);对照组并发应激性溃疡出血及病死分别为21例(42.9%)和11例(22.4%)。2组应激性溃疡发生率和病死率比较均有显著性差异(P均<0.01)。结论:“白黄液”能有效地预防应激性溃疡出血的发生,降低病死率,为预防脑出血并发应激性溃疡出血和降低病死率的有效药物,值得推广使用。
Objective: To observe the curative effect of traditional Chinese medicine “Baihuang liquid” in preventing cerebral hemorrhage complicated with stress ulcer bleeding. Methods: One hundred and ten patients with intracerebral hemorrhage were randomly divided into observation group (n = 61) and control group (n = 49). The observation group was given “Baihuang liquid” by oral or gastric tube in the control group. Results: In the observation group, 5 patients (8.2%) had ulcer bleeding and 4 patients died (6.6%). In the control group, 21 patients (42.9%) had bleeding and died of stress ulcer Eleven patients (22.4%). There was a significant difference between the two groups in the incidence of stress ulcer and mortality (P <0.01). Conclusion: “Baihuang Liquid” can effectively prevent the occurrence of stress ulcer hemorrhage and reduce the mortality. It is worth promoting for the prevention of cerebral hemorrhage complicated with ulcer bleeding and mortality.