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地尔硫与噻嗪类利尿剂、肾上腺素β受体阻滞剂和血管紧张素转换酶抑制剂比较,虽都有降低血压作用,但噻嗪类利尿剂可引起血钾降低,血糖增加;普萘洛尔可增强胰岛素的降血糖作用和延缓血糖的恢复,增高血脂作用等;而地尔硫(艹卓)没有发现上述代谢方面的不利影响,相反,降压作用比转换酶抑制剂更持久,同时伴心脏保护作用,副作用小,为适合老年高血压病人单用的首选药物。
Diltiazem and thiazide diuretics, adrenergic β-blockers and angiotensin-converting enzyme inhibitors, although all have lower blood pressure, but thiazide diuretics can cause decreased serum potassium, increased blood sugar ; Propranolol can enhance the hypoglycemic effect of insulin and delay the recovery of blood glucose, increase blood lipids, etc .; and diltiazem did not find the above adverse effects of metabolism, on the contrary, antihypertensive effect than the conversion enzyme inhibitor More lasting, at the same time with cardioprotection, side effects, suitable for elderly patients with hypertension preferred drug alone.