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目的为了解肾移植受者子代的状况,以有助于指导肾移植受者生育及子代的成长。方法以本中心21例肾移植受者子代为研究对象,采用直接询问肾移植受者的方式调查术后生育对胎儿的影响、喂养方式等情况,测量身高、体重,测定血红蛋白含量、血肌酐值、尿红细胞数量及尿蛋白值,评定社会生活能力及智力水平。结果男性肾移植受者的生育对胎儿似无明显影响,以母乳喂养为首选喂养方式;女性肾移植受者的妊娠结局可以接受,选择了人工喂养。男女受者所生子女总体具有良好的运动能力、身体抵抗力、生长发育水平、社会生活能力及智力水平,具有正常的肾功能,同时也存在营养不良与营养过剩问题。结论肾移植受者可以怀孕,可以生育出健康子代,子代成长可以同正常人群,但妊娠仍存在较高风险,还需进一步研究对子代的远期影响。
Objective To understand the status of offspring of kidney transplant recipients to help guide the growth of kidney transplant recipients and their offspring. Methods The offspring of 21 renal transplant recipients in our center were investigated. The effects of postoperative fertilization on the fetus and feeding methods were investigated by direct interrogation of renal transplant recipients. Height, weight, hemoglobin, serum creatinine , Urinary red blood cell count and urine protein value, assessment of social viability and intelligence level. Results Male kidney transplant recipients had no significant effect on the fetus, breastfeeding as the preferred method of feeding; female kidney transplant recipients of pregnancy outcome was acceptable, chose artificial feeding. The children born to both men and women generally have good athletic ability, body resistance, growth and development, social viability and intellectual ability, normal kidney function, and malnutrition and overnutrition. Conclusion Kidney transplant recipients can be pregnant and can give birth to healthy offspring. Their offspring can grow in the same population as their normal counterparts. However, there is still a high risk of pregnancy, and the long-term impact on offspring needs to be further studied.