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目的探讨应用米非司酮治疗子宫肌瘤的临床效果。方法选择2006年7月至2007年8月本院门诊经妇科检查及B超确诊的子宫肌瘤患者80例,自月经第5～6天开始口服米非司酮l0mg/d,观察疗效和不良反应。结果用药3个月后,患者子宫及肌瘤体积均明显缩小,治疗总有效率为88.8%;用药后出现轻度恶心4例,10例出现轻微潮热症状,轻微阴道分泌物减少3例,无体质量增加及肝肾功能损害。结论米非司酮治疗子宫肌瘤是一种较理想的药物。
Objective To investigate the clinical effect of mifepristone in treating uterine fibroids. Methods From July 2006 to August 2007, 80 outpatients with uterine fibroids diagnosed by gynecological examination and B-ultrasound were selected. Oral mifepristone (10 mg / d) was administered orally from the 5th to 6th day of menstruation to observe the curative effect and adverse effects reaction. Results After 3 months of treatment, the volume of uterus and fibroids were significantly reduced, the total effective rate was 88.8%; mild nausea occurred in 4 cases after treatment, mild hot flashes in 10 cases, slight vaginal discharge in 3 cases, No increase in body mass and liver and kidney dysfunction. Conclusion Mifepristone treatment of uterine fibroids is a more ideal drug.