临床报道当归芍药散能够改善神经功能障碍,如治疗阿耳茨海默病、老年性痴呆和记忆缺失等。在体和离体实验的临床前研究表明,该方可改善学习和记忆功能,并对谷氨酸盐(Glu)引起的神经死亡有保护作用。然而该方对中枢神经功能障碍的保护作用还不清楚。因此,探讨该药的作用机制对中药治疗神经系统疾病有重要意义。 Clinically reported that Danggui Shaoyao Powder can improve neurological dysfunction, such as the treatment of Alzheimer’s disease, senile dementia and memory loss. Preclinical studies in in vivo and ex vivo experiments have shown that this formula can improve learning and memory function and protect against glutamate (Glu)-induced neuronal death. However, the protective effect of this party on central nervous system dysfunction is still unclear. Therefore, to explore the mechanism of action of this drug is of great significance for the treatment of nervous system diseases by traditional Chinese medicine.