感染人类免疫缺陷病毒(human immunodeficiency virus,HIV)的患者可有各种胃肠道症状,包括慢性腹泻。人T细胞、巨噬细胞以及精液等几种体液中曾发现有感染性HIV。鉴于在有些伴慢性腹泻血清HIV阳性的患者,未能找到胃肠道病原体,作者研究HIV直接感染肠组织的可能性。对象与方法:研究对象包括有慢性腹泻史HIV感染13例,无胃肠道症状血清HIV阳性1例,均作内镜活组织检查。 Patients infected with the human immunodeficiency virus (HIV) can have a variety of gastrointestinal symptoms, including chronic diarrhea. Human T cells, macrophages and semen and other fluids have been found to have infectious HIV. In view of the failure to find a gastrointestinal pathogen in some HIV-positive patients with chronic diarrhea serums, the authors investigated the potential for HIV to directly infect intestinal tissue. Subjects and Methods: Participants included 13 HIV-infected patients with a history of chronic diarrhea, 1 HIV-positive serum without gastrointestinal symptoms, and all had endoscopic biopsy.