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目的分析2005—2014年江阴市伤寒副伤寒流行规律,为制定全市防治策略提供依据。方法对收集的疫情资料进行回顾性分析。结果江阴市2005—2014年江阴市伤寒副伤寒年平均发病率为1.41/10万,发病高峰在4—10月,具有春、夏发病高峰趋势,男女发病率差异无统计学意义,发病率以0~4岁组最高,学生、农民、散居儿童和工人为高危人群,高发地区为流动人口比较集中的乡镇、街道。病原谱以伤寒沙门菌为主(100%),血培养分离菌株阳性率(0.39%)高于粪便培养(0.25%)。药敏分析利福平(100%)和杆菌肽(91.67%)耐药率高,其次为萘啶酸(73.91%)、复方新诺明(72.73%),多重耐药率为50%。结论江阴市伤寒疫情呈下降趋势并稳定在较低水平,副伤寒疫情有可能面临上升的可能,需采取针对性健康教育和加强疾病监测工作等综合性防控措施来进一步控制伤寒副伤寒发病率,防止暴发疫情的发生。
Objective To analyze the prevalence of typhoid and paratyphoid fever in Jiangyin City from 2005 to 2014 and provide the basis for the prevention and control strategy in the city. Methods The collected epidemic data were retrospectively analyzed. Results The average incidence of typhoid and paratyphoid fever in Jiangyin from 2005 to 2014 was 1.41 / lakh and the peak incidence peak was from April to October with the peak trend of spring and summer onset. There was no significant difference between male and female incidence rates 0 to 4 years old group is the highest, students, peasants, scattered children and workers are high risk groups, high incidence areas are the towns and streets where the floating population is concentrated. Pathogenic spectrum of Salmonella typhi mainly (100%), blood culture isolates positive rate (0.39%) higher than the stool culture (0.25%). Drug susceptibility analysis Rifampicin (100%) and bacitracin (91.67%) had a high resistance rate, followed by nalidixic acid (73.91%), cotrimoxazole (72.73%) and multi-drug resistance rate 50%. Conclusion The epidemic situation of typhoid fever in Jiangyin shows a decreasing trend and is stable at a low level. Paratyphoid epidemic situation may be facing the possibility of rising. Comprehensive prevention and control measures such as targeted health education and disease surveillance are needed to further control the incidence of typhoid and paratyphoid fever , To prevent the outbreak of the outbreak.