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目的 研究微波辐射对金地鼠颊囊白斑癌变的阻断效果。方法 采用金地鼠77只， 随机分为三组。微波处理组(51只)， 以0.5%二甲基苯并蒽(DMBA)涂布颊囊5 w， 从第6周起每周1次以微波功率Ⅱ档、时间2 s或3 s辐射颊囊涂布区1～6次。完成预定辐射后观察12 w。空白对照组(6只)和模型对照组(20只)分别以生理盐水和0.5% DMBA涂布颊囊5 w后观察12 w， 均不经微波处理。结果 实验结束时微波处理组均质状白斑、颗粒状白斑和肿瘤的发生率分别为6.9%、12.5%、1.4%， 而模型对照组的相应发生率则分别为25.0%、47.2%、22.2%， 两组间差异有高度显著性(P＜0.01)。结论 微波辐射能有效地降低金地鼠颊囊白斑发生率及阻断白斑癌变。
Objective To study the effect of microwave radiation on the leukoplakia of hamster cheek pouch. Methods 77 golden hamsters were randomly divided into three groups. The rats in the microwave treatment group (51) were treated with 0.5% dimethylbenz (a) anthracene (DMBA) for 5 weeks, and the cheek pouch was irradiated once a week for 2 weeks or 2 s Capsule coating area 1 to 6 times. After completion of the scheduled radiation observation 12 w. The blank control group (n = 6) and the model control group (n = 20) were treated with saline and 0.5% DMBA for 5 weeks respectively and were observed for 12 weeks without microwave treatment. Results The incidences of leukoplakia, leukoplakia and tumor in the microwave treatment group were 6.9%, 12.5% and 1.4% respectively at the end of the experiment, while those in the model control group were 25.0%, 47.2% and 22.2% The differences between the two groups were highly significant (P <0.01). Conclusion Microwave radiation can effectively reduce the incidence of leukoplakia in white ghouls and block the carcinogenesis of white spots.