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目的:探讨肝胆管囊腺瘤(IBCA)临床特点,为临床诊断与治疗提供参考。方法:收集15年来发表的关于IBCA临床文章,共计151例患者,对患者的诊断、治疗方法及预后等进行分析。结果:151例IBCA患者中81例术前被误诊,误诊率达53.6%,其中23例个案报告的误诊率为91.3%;患者平均年龄为49.5岁,女性明显多于男性(4.3:1),病程一般多在6年左右,发病部位左肝多于右肝(1.4:1);早期影像学检查和实验室检查特异性不强;手术全切后随访多数预后良好,有部分癌变。结论:IBCA临床表现无特异性,术前容易误诊,术中快速病理切片尤为必要,手术切除为主要治疗方法;IBCA有恶变倾向,术中尽量行肿瘤全切。
Objective: To investigate the clinical features of hepatobiliary cystadenoma (IBCA) and provide reference for clinical diagnosis and treatment. METHODS: Fifteen clinical articles published in the past 15 years were collected for a total of 151 patients, and their diagnosis, treatment and prognosis were analyzed. Results: Among 151 IBCA patients, 81 cases were misdiagnosed preoperatively with a misdiagnosis rate of 53.6%. The misdiagnosis rate of 91 cases was reported in 23 cases. The mean age of patients was 49.5 years old, significantly more than that of men (4.3: 1) The course of disease was generally more than 6 years, the incidence of left liver more than the right liver (1.4: 1); early imaging and laboratory tests specificity is not strong; the majority of follow-up after surgery, most of the prognosis is good, some cancer. Conclusion: IBCA has no specific clinical manifestations. It is easy to misdiagnose before operation. The rapid intraoperative pathological section is necessary and surgical resection is the main treatment method. IBCA has malignant tendency.